1978 Week 2
| Sep 9, 1978 | ||
| Detroit Lions | 15 | Final |
| Tampa Bay Buccaneers | 7 | |
| PassYds | Landry-DET | 55 |
| RushYds | Bell-TAM | 98 |
| RecYds | Giles-TAM | 37 |
| Sep 10, 1978 | ||
| New Orleans Saints | 17 | Final |
| Green Bay Packers | 28 | |
| PassYds | Manning-NOR | 303 |
| RushYds | Middleton-GNB | 114 |
| RecYds | Galbreath-NOR | 122 |
| Sep 10, 1978 | ||
| Dallas Cowboys | 34 | Final |
| New York Giants | 24 | |
| PassYds | Pisarcik-NYG | 261 |
| RushYds | Dorsett-DAL | 111 |
| RecYds | Robinson-NYG | 100 |
| Sep 10, 1978 | ||
| Seattle Seahawks | 10 | Final |
| Pittsburgh Steelers | 21 | |
| PassYds | Bradshaw-PIT | 213 |
| RushYds | Harris-PIT | 64 |
| RecYds | Largent-SEA | 88 |
| Sep 10, 1978 | ||
| Philadelphia Eagles | 30 | Final |
| Washington Redskins | 35 | |
| PassYds | Theismann-WAS | 226 |
| RushYds | Montgomery-PHI | 87 |
| RecYds | Carmichael-PHI | 81 |
| Sep 10, 1978 | ||
| Cincinnati Bengals | 10 | Final |
| Cleveland Browns | 13 | OT |
| PassYds | Sipe-CLE | 219 |
| RushYds | Pruitt-CLE | 120 |
| RecYds | Rucker-CLE | 77 |
| Sep 10, 1978 | ||
| New England Patriots | 16 | Final |
| St. Louis Cardinals | 6 | |
| PassYds | Grogan-NWE | 172 |
| RushYds | Calhoun-NWE | 143 |
| RecYds | Francis-NWE | 74 |
| Sep 10, 1978 | ||
| Houston Oilers | 20 | Final |
| Kansas City Chiefs | 17 | |
| PassYds | Livingston-KAN | 60 |
| RushYds | Reed-KAN | 141 |
| RecYds | Reed-KAN | 31 |
| Sep 10, 1978 | ||
| New York Jets | 21 | Final |
| Buffalo Bills | 20 | |
| PassYds | Ferguson-BUF | 222 |
| RushYds | Long-NYJ | 75 |
| RecYds | Gaffney-NYJ | 108 |
| Sep 10, 1978 | ||
| Miami Dolphins | 42 | Final |
| Baltimore Colts | 0 | |
| PassYds | Troup-BAL | 186 |
| RushYds | Harris-MIA | 79 |
| RecYds | Doughty-BAL | 69 |
| Sep 10, 1978 | ||
| Atlanta Falcons | 0 | Final |
| Los Angeles Rams | 10 | |
| PassYds | Haden-RAM | 237 |
| RushYds | Cappelletti-RAM | 57 |
| RecYds | Miller-RAM | 88 |
| Sep 10, 1978 | ||
| Oakland Raiders | 21 | Final |
| San Diego Chargers | 20 | |
| PassYds | Stabler-OAK | 307 |
| RushYds | Matthews-SDG | 78 |
| RecYds | Bradshaw-OAK | 107 |
| Sep 10, 1978 | ||
| Chicago Bears | 16 | Final |
| San Francisco 49ers | 13 | |
| PassYds | Avellini-CHI | 115 |
| RushYds | Simpson-SFO | 108 |
| RecYds | Scott-CHI | 87 |
| Sep 11, 1978 | ||
| Denver Broncos | 9 | Final |
| Minnesota Vikings | 12 | OT |
| PassYds | Tarkenton-MIN | 98 |
| RushYds | Armstrong-DEN | 64 |
| RecYds | Moses-DEN | 53 |
1978 Week Summaries