1978 Week 1
| Sep 2, 1978 | ||
| New York Giants | 19 | Final |
| Tampa Bay Buccaneers | 13 | |
| PassYds | Pisarcik-NYG | 156 |
| RushYds | Bell-TAM | 54 |
| RecYds | Perkins-NYG | 110 |
| Sep 3, 1978 | ||
| Houston Oilers | 14 | Final |
| Atlanta Falcons | 20 | |
| PassYds | Pastorini-HOU | 136 |
| RushYds | Campbell-HOU | 137 |
| RecYds | Burrough-HOU | 56 |
| Sep 3, 1978 | ||
| Pittsburgh Steelers | 28 | Final |
| Buffalo Bills | 17 | |
| PassYds | Bradshaw-PIT | 217 |
| RushYds | Harris-PIT | 96 |
| RecYds | Miller-BUF | 97 |
| Sep 3, 1978 | ||
| Kansas City Chiefs | 24 | Final |
| Cincinnati Bengals | 23 | |
| PassYds | Reaves-CIN | 159 |
| RushYds | Bailey-KAN | 106 |
| RecYds | White-KAN | 57 |
| Sep 3, 1978 | ||
| San Francisco 49ers | 7 | Final |
| Cleveland Browns | 24 | |
| PassYds | Sipe-CLE | 190 |
| RushYds | Pruitt-CLE | 106 |
| RecYds | Rucker-CLE | 113 |
| Sep 3, 1978 | ||
| Green Bay Packers | 13 | Final |
| Detroit Lions | 7 | |
| PassYds | Landry-DET | 116 |
| RushYds | Middleton-GNB | 91 |
| RecYds | Hill-DET | 64 |
| Sep 3, 1978 | ||
| Minnesota Vikings | 24 | Final |
| New Orleans Saints | 31 | |
| PassYds | Tarkenton-MIN | 282 |
| RushYds | Foreman-MIN | 122 |
| RecYds | Young-MIN | 134 |
| Sep 3, 1978 | ||
| Washington Redskins | 16 | Final |
| New England Patriots | 14 | |
| PassYds | Grogan-NWE | 199 |
| RushYds | Ivory-NWE | 89 |
| RecYds | Jackson-NWE | 124 |
| Sep 3, 1978 | ||
| Miami Dolphins | 20 | Final |
| New York Jets | 33 | |
| PassYds | Todd-NYJ | 245 |
| RushYds | Williams-MIA | 119 |
| RecYds | Walker-NYJ | 108 |
| Sep 3, 1978 | ||
| Los Angeles Rams | 16 | Final |
| Philadelphia Eagles | 14 | |
| PassYds | Haden-RAM | 154 |
| RushYds | Montgomery-PHI | 46 |
| RecYds | Miller-RAM | 44 |
| Sep 3, 1978 | ||
| St. Louis Cardinals | 10 | Final |
| Chicago Bears | 17 | |
| PassYds | Hart-STL | 152 |
| RushYds | Payton-CHI | 101 |
| RecYds | Gray-STL | 83 |
| Sep 3, 1978 | ||
| Oakland Raiders | 6 | Final |
| Denver Broncos | 14 | |
| PassYds | Stabler-OAK | 212 |
| RushYds | van Eeghen-OAK | 89 |
| RecYds | Branch-OAK | 58 |
| Sep 3, 1978 | ||
| San Diego Chargers | 24 | Final |
| Seattle Seahawks | 20 | |
| PassYds | Zorn-SEA | 329 |
| RushYds | Sims-SEA | 61 |
| RecYds | Largent-SEA | 127 |
| Sep 4, 1978 | ||
| Baltimore Colts | 0 | Final |
| Dallas Cowboys | 38 | |
| PassYds | Staubach-DAL | 280 |
| RushYds | Dorsett-DAL | 147 |
| RecYds | Dorsett-DAL | 107 |
1978 Week Summaries