1980 Week 16
| Dec 20, 1980 | ||
| New York Jets | 24 | Final |
| Miami Dolphins | 17 | |
| PassYds | Woodley-MIA | 223 |
| RushYds | Nathan-MIA | 97 |
| RecYds | Walker-NYJ | 91 |
| Dec 20, 1980 | ||
| Chicago Bears | 14 | Final |
| Tampa Bay Buccaneers | 13 | |
| PassYds | Williams-TAM | 350 |
| RushYds | Payton-CHI | 130 |
| RecYds | House-TAM | 138 |
| Dec 21, 1980 | ||
| Cleveland Browns | 27 | Final |
| Cincinnati Bengals | 24 | |
| PassYds | Sipe-CLE | 308 |
| RushYds | Pruitt-CLE | 51 |
| RecYds | McInally-CIN | 86 |
| Dec 21, 1980 | ||
| Washington Redskins | 31 | Final |
| St. Louis Cardinals | 7 | |
| PassYds | Theismann-WAS | 260 |
| RushYds | Hammond-WAS | 135 |
| RecYds | Monk-WAS | 95 |
| Dec 21, 1980 | ||
| Green Bay Packers | 3 | Final |
| Detroit Lions | 24 | |
| PassYds | Danielson-DET | 219 |
| RushYds | Bussey-DET | 68 |
| RecYds | Scott-DET | 75 |
| Dec 21, 1980 | ||
| New England Patriots | 38 | Final |
| New Orleans Saints | 27 | |
| PassYds | Manning-NOR | 301 |
| RushYds | Calhoun-NWE | 113 |
| RecYds | Chandler-NOR | 98 |
| Dec 21, 1980 | ||
| Oakland Raiders | 33 | Final |
| New York Giants | 17 | |
| PassYds | Plunkett-OAK | 164 |
| RushYds | van Eeghen-OAK | 115 |
| RecYds | Chandler-OAK | 72 |
| Dec 21, 1980 | ||
| Minnesota Vikings | 16 | Final |
| Houston Oilers | 20 | |
| PassYds | Kramer-MIN | 266 |
| RushYds | Campbell-HOU | 203 |
| RecYds | Casper-HOU | 120 |
| Dec 21, 1980 | ||
| Kansas City Chiefs | 38 | Final |
| Baltimore Colts | 28 | |
| PassYds | Kenney-KAN | 316 |
| RushYds | Dickey-BAL | 65 |
| RecYds | Marshall-KAN | 176 |
| Dec 21, 1980 | ||
| Philadelphia Eagles | 27 | Final |
| Dallas Cowboys | 35 | |
| PassYds | Jaworski-PHI | 331 |
| RushYds | Dorsett-DAL | 74 |
| RecYds | Hill-DAL | 110 |
| Dec 21, 1980 | ||
| Atlanta Falcons | 17 | Final |
| Los Angeles Rams | 20 | OT |
| PassYds | Bartkowski-ATL | 225 |
| RushYds | Thomas-RAM | 144 |
| RecYds | Dennard-RAM | 96 |
| Dec 21, 1980 | ||
| Denver Broncos | 25 | Final |
| Seattle Seahawks | 17 | |
| PassYds | Zorn-SEA | 222 |
| RushYds | Lytle-DEN | 89 |
| RecYds | Largent-SEA | 70 |
| Dec 21, 1980 | ||
| Buffalo Bills | 18 | Final |
| San Francisco 49ers | 13 | |
| PassYds | Montana-SFO | 163 |
| RushYds | Cribbs-BUF | 128 |
| RecYds | Elliott-SFO | 66 |
| Dec 22, 1980 | ||
| Pittsburgh Steelers | 17 | Final |
| San Diego Chargers | 26 | |
| PassYds | Fouts-SDG | 308 |
| RushYds | Muncie-SDG | 115 |
| RecYds | Winslow-SDG | 171 |
1980 Week Summaries