Starters
- *ProBowl, +1st-tm All-Pro
| Pos | Player | Age | Yrs | GS | Summary of Player Stats | Drafted (tm/rnd/yr) |
|---|---|---|---|---|---|---|
| Offensive Starters | ||||||
| QB | Marc Bulger | 32 | 7 | 8 | 140 for 247, 1,469 yards, 5 td, 6 int, & 8 rushes for 22 yards and 0 td | |
| RB | Steven Jackson* | 26 | 5 | 15 | 324 rushes for 1,416 yards, 4 td, & 51 catches for 322 yards and 0 td | |
| FB | Mike Karney | 28 | 5 | 8 | 2 rushes for 8 yards, 0 td, & 6 catches for 16 yards and 0 td | |
| WR | Donnie Avery | 25 | 1 | 16 | 47 catches for 589 yards, 5 td, & 4 rushes for 30 yards and 0 td | |
| WR | Keenan Burton | 25 | 1 | 6 | 25 catches for 253 yards, 0 td | |
| TE | Randy McMichael | 30 | 7 | 16 | 34 catches for 332 yards, 1 td | |
| LT | Alex Barron | 27 | 4 | 16 | ||
| LG | Jacob Bell | 28 | 5 | 13 | ||
| C | Jason Brown | 26 | 4 | 16 | ||
| RG | Richie Incognito | 26 | 3 | 9 | ||
| RT | Adam Goldberg | 29 | 5 | 14 | 1 fumble recovered | |
| Defensive Starters | ||||||
| LDE | Leonard Little | 35 | 11 | 13 | 6.5 sacks, 1 interception, 0 fumbles recovered | |
| LDT | Gary Gibson | 27 | 2 | 5 | ||
| RDT | Clifton Ryan | 25 | 2 | 15 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RDE | James Hall | 32 | 9 | 14 | 4.5 sacks, 0 interceptions, 0 fumbles recovered | |
| LLB | David Vobora | 23 | 1 | 10 | ||
| MLB | James Laurinaitis | 23 | Rook | 16 | 2.0 sacks, 2 interceptions, 1 fumble recovered | |
| RLB | Paris Lenon | 32 | 7 | 10 | ||
| LCB | Ron Bartell | 27 | 4 | 15 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
| RCB | Quincy Butler | 26 | 3 | 7 | ||
| SS | James Butler | 27 | 4 | 13 | 0.0 sacks, 3 interceptions, 1 fumble recovered | |
| FS | O.J. Atogwe | 28 | 4 | 12 | 1.0 sacks, 2 interceptions, 2 fumbles recovered |
Roster