| Offensive Starters | | | | | |
|---|
| QB | Will Levis | 24 | Rook | 9 | 149 for 255, 1,808 yards, 8 td, 4 int, & 25 rushes for 57 yards and 1 td | |
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| RB | Derrick Henry* | 29 | 7 | 17 | 280 rushes for 1,167 yards, 12 td, & 28 catches for 214 yards and 0 td | |
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| WR | Treylon Burks | 23 | 1 | 9 | 16 catches for 221 yards, 0 td, & 5 rushes for 18 yards and 0 td | |
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| WR | DeAndre Hopkins | 31 | 10 | 16 | 75 catches for 1,057 yards, 7 td, & 2 rushes for 9 yards and 0 td | |
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| TE | Chigoziem Okonkwo | 24 | 1 | 11 | 54 catches for 528 yards, 1 td, & 2 rushes for 6 yards and 0 td | |
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| TE | Trevon Wesco | 28 | 4 | 10 | 1 catch for 21 yards, 0 td | |
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| LT | Andre Dillard | 28 | 4 | 10 | | |
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| LG | Peter Skoronski | 22 | Rook | 14 | | |
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| C | Aaron Brewer | 26 | 3 | 17 | | |
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| RG | Daniel Brunskill | 29 | 4 | 14 | | |
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| RT | Chris Hubbard | 32 | 9 | 9 | | |
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| Defensive Starters | | | | | |
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| LDE | Denico Autry | 33 | 9 | 14 | 11.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LDT | Teair Tart | 26 | 3 | 9 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDT | Jeffery Simmons | 26 | 4 | 12 | 5.5 sacks, 0 interceptions, 1 fumble recovered | |
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| RDE | Kyle Peko | 30 | 7 | 10 | | |
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| LILB | Azeez Al-Shaair | 26 | 4 | 17 | 2.0 sacks, 0 interceptions, 1 fumble recovered | |
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| RILB | Jack Gibbens | 25 | 1 | 13 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| ROLB | Harold Landry | 27 | 5 | 10 | 10.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LCB | Sean Murphy-Bunting | 26 | 4 | 14 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
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| SS | K'Von Wallace | 26 | 3 | 7 | | |
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| FS | Amani Hooker | 25 | 4 | 13 | 0.0 sacks, 1 interception, 1 fumble recovered | |
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Roster