| Offensive Starters | | | | | |
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| QB | Matt Hasselbeck* | 32 | 8 | 16 | 352 for 562, 3,966 yards, 28 td, 12 int, & 39 rushes for 89 yards and 0 td | |
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| RB | Shaun Alexander | 30 | 7 | 10 | 207 rushes for 716 yards, 4 td, & 14 catches for 76 yards and 1 td | |
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| WR | Deion Branch | 28 | 5 | 11 | 49 catches for 661 yards, 4 td | |
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| WR | Nate Burleson | 26 | 4 | 12 | 50 catches for 694 yards, 9 td, & 2 rushes for 4 yards and 0 td | |
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| WR | Bobby Engram | 34 | 11 | 13 | 94 catches for 1,147 yards, 6 td | |
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| TE | Marcus Pollard | 35 | 12 | 10 | 28 catches for 273 yards, 2 td | |
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| LT | Walter Jones*+ | 33 | 10 | 15 | | |
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| LG | Rob Sims | 24 | 1 | 16 | | |
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| C | Chris Spencer | 25 | 2 | 16 | | |
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| RG | Chris Gray | 37 | 14 | 16 | | |
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| RT | Sean Locklear | 26 | 3 | 16 | 2 fumbles recovered | |
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| Defensive Starters | | | | | |
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| LDE | Patrick Kerney*+ | 31 | 8 | 16 | 14.5 sacks, 1 interception, 0 fumbles recovered | |
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| LDT | Brandon Mebane | 22 | Rook | 10 | 2.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| RDT | Rocky Bernard | 28 | 5 | 14 | 3.5 sacks, 0 interceptions, 2 fumbles recovered | |
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| RDE | Darryl Tapp | 23 | 1 | 16 | 7.0 sacks, 1 interception, 2 fumbles recovered | |
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| LLB | LeRoy Hill | 25 | 2 | 14 | 3.0 sacks, 0 interceptions, 1 fumble recovered | |
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| MLB | Lofa Tatupu*+ | 25 | 2 | 16 | 1.0 sacks, 4 interceptions, 0 fumbles recovered | |
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| RLB | Julian Peterson* | 29 | 7 | 16 | 9.5 sacks, 2 interceptions, 2 fumbles recovered | |
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| LCB | Marcus Trufant* | 27 | 4 | 16 | 0.0 sacks, 7 interceptions, 0 fumbles recovered | |
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| RCB | Kelly Jennings | 25 | 1 | 15 | 0.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| SS | Deon Grant | 28 | 6 | 16 | 0.0 sacks, 3 interceptions, 1 fumble recovered | |
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| FS | Brian Russell | 29 | 5 | 16 | 1.0 sacks, 1 interception, 1 fumble recovered | |
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Roster