| Offensive Starters | | | | | |
|---|
| QB | Justin Herbert | 25 | 3 | 13 | 297 for 456, 3,134 yards, 20 td, 7 int, & 52 rushes for 228 yards and 3 td | |
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| RB | Austin Ekeler | 28 | 6 | 14 | 179 rushes for 628 yards, 5 td, & 51 catches for 436 yards and 1 td | |
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| WR | Keenan Allen* | 31 | 10 | 13 | 108 catches for 1,243 yards, 7 td, & 2 rushes for 6 yards and 0 td | |
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| WR | Quentin Johnston | 22 | Rook | 10 | 38 catches for 431 yards, 2 td, & 3 rushes for 9 yards and 0 td | |
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| TE | Gerald Everett | 29 | 6 | 12 | 51 catches for 411 yards, 3 td, & 3 rushes for 10 yards and 0 td | |
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| TE | Donald Parham | 26 | 3 | 8 | 27 catches for 285 yards, 4 td | |
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| LT | Rashawn Slater | 24 | 2 | 17 | | |
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| LG | Zion Johnson | 24 | 1 | 15 | | |
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| C | Will Clapp | 28 | 5 | 11 | | |
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| RG | Jamaree Salyer | 23 | 1 | 17 | | |
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| RT | Trey Pipkins | 27 | 4 | 17 | | |
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| Defensive Starters | | | | | |
|---|
| LDE | Sebastian Joseph-Day | 28 | 4 | 14 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| NT | Nick Williams | 33 | 9 | 6 | 1.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| RDE | Austin Johnson | 29 | 7 | 17 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
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| LOLB | Khalil Mack* | 32 | 9 | 17 | 17.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| LILB | Eric Kendricks | 31 | 8 | 14 | 3.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| RILB | Kenneth Murray | 25 | 3 | 15 | 3.0 sacks, 1 interception, 0 fumbles recovered | |
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| ROLB | Tuli Tuipulotu | 21 | Rook | 11 | 4.5 sacks, 0 interceptions, 1 fumble recovered | |
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| LCB | Asante Samuel Jr. | 24 | 2 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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| RCB | Michael Davis | 28 | 6 | 13 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
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| SS | Alohi Gilman | 26 | 3 | 14 | 0.0 sacks, 2 interceptions, 2 fumbles recovered | |
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| FS | Derwin James | 27 | 5 | 16 | 2.0 sacks, 1 interception, 2 fumbles recovered | |
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Roster