| Offensive Starters | | | | | |
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| QB | Drew Brees | 41 | 19 | 12 | 275 for 390, 2,942 yards, 24 td, 6 int, & 18 rushes for -2 yards and 2 td | San Diego Chargers / 2nd / 32nd pick / 2001 |
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| RB | Alvin Kamara * | 25 | 3 | 10 | 187 rushes for 932 yards, 16 td, & 83 catches for 756 yards and 5 td | New Orleans Saints / 3rd / 67th pick / 2017 |
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| fb | Michael Burton | 28 | 5 | 4 | | Detroit Lions / 5th / 168th pick / 2015 |
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| wr | Emmanuel Sanders | 33 | 10 | 5 | | Pittsburgh Steelers / 3rd / 82nd pick / 2010 |
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| WR | Tre'Quan Smith | 24 | 2 | 10 | 34 catches for 448 yards, 4 td, & 1 rush for 3 yards and 0 td | New Orleans Saints / 3rd / 91st pick / 2018 |
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| te | Jared Cook | 33 | 11 | 5 | | Tennessee Titans / 3rd / 89th pick / 2009 |
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| LT | Terron Armstead* | 29 | 7 | 14 | | New Orleans Saints / 3rd / 75th pick / 2013 |
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| LG | Andrus Peat* | 27 | 5 | 13 | 1 fumble recovered | New Orleans Saints / 1st / 13th pick / 2015 |
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| C | Erik McCoy | 23 | 1 | 16 | | New Orleans Saints / 2nd / 48th pick / 2019 |
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| RG | Cesar Ruiz | 21 | Rook | 9 | | New Orleans Saints / 1st / 24th pick / 2020 |
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| RT | Ryan Ramczyk | 26 | 3 | 16 | | New Orleans Saints / 1st / 32nd pick / 2017 |
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| Defensive Starters | | | | | |
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| LDE | Cameron Jordan* | 31 | 9 | 16 | 7.5 sacks, 0 interceptions, 0 fumbles recovered | New Orleans Saints / 1st / 24th pick / 2011 |
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| LDT | David Onyemata | 28 | 4 | 15 | 6.5 sacks, 1 interception, 0 fumbles recovered | New Orleans Saints / 4th / 120th pick / 2016 |
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| RDT | Malcom Brown | 26 | 5 | 13 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | New England Patriots / 1st / 32nd pick / 2015 |
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| RDE | Trey Hendrickson | 26 | 3 | 15 | 13.5 sacks, 0 interceptions, 0 fumbles recovered | New Orleans Saints / 3rd / 103rd pick / 2017 |
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| llb | Kwon Alexander | 26 | 5 | 7 | | Tampa Bay Buccaneers / 4th / 124th pick / 2015 |
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| MLB | Demario Davis | 31 | 8 | 16 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | New York Jets / 3rd / 77th pick / 2012 |
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| LCB | Janoris Jenkins | 32 | 8 | 13 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | St. Louis Rams / 2nd / 39th pick / 2012 |
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| RCB | Marshon Lattimore * | 24 | 3 | 14 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | New Orleans Saints / 1st / 11th pick / 2017 |
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| SS | Malcolm Jenkins | 33 | 11 | 16 | 2.5 sacks, 3 interceptions, 1 fumble recovered | New Orleans Saints / 1st / 14th pick / 2009 |
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| FS | Marcus Williams | 24 | 3 | 14 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | New Orleans Saints / 2nd / 42nd pick / 2017 |
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| DB | Chauncey Gardner-Johnson | 23 | 1 | 13 | | New Orleans Saints / 4th / 105th pick / 2019 |
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Roster