| Offensive Starters | | | | | |
|---|
| QB | Matthew Stafford | 23 | 2 | 16 | 421 for 663, 5,038 yards, 41 td, 16 int, & 22 rushes for 78 yards and 0 td | |
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| RB | Jahvid Best | 22 | 1 | 6 | 84 rushes for 390 yards, 2 td, & 27 catches for 287 yards and 1 td | |
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| WR | Nate Burleson | 30 | 8 | 11 | 73 catches for 757 yards, 3 td, & 11 rushes for 85 yards and 0 td | |
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| WR | Calvin Johnson*+ | 26 | 4 | 16 | 96 catches for 1,681 yards, 16 td, & 1 rush for 11 yards and 0 td | |
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| WR | Titus Young | 22 | Rook | 9 | 48 catches for 607 yards, 6 td, & 2 rushes for 15 yards and 0 td | |
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| TE | Brandon Pettigrew | 26 | 2 | 16 | 83 catches for 777 yards, 5 td | |
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| LT | Jeff Backus | 34 | 10 | 16 | 1 fumble recovered | |
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| LG | Rob Sims | 28 | 5 | 16 | 1 fumble recovered | |
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| C | Dominic Raiola | 33 | 10 | 16 | | |
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| RG | Stephen Peterman | 29 | 6 | 16 | | |
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| RT | Gosder Cherilus | 27 | 3 | 15 | | |
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| Defensive Starters | | | | | |
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| LDE | Cliff Avril | 25 | 3 | 16 | 11.0 sacks, 1 interception, 3 fumbles recovered | |
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| LDT | Ndamukong Suh | 24 | 1 | 14 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDT | Corey Williams | 31 | 7 | 15 | 2.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDE | Kyle Vanden Bosch | 33 | 10 | 16 | 8.0 sacks, 0 interceptions, 1 fumble recovered | |
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| LLB | Justin Durant | 26 | 4 | 12 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| MLB | Stephen Tulloch | 26 | 5 | 16 | 3.0 sacks, 2 interceptions, 3 fumbles recovered | |
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| RLB | DeAndre Levy | 24 | 2 | 16 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
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| LCB | Chris Houston | 27 | 4 | 13 | 0.0 sacks, 5 interceptions, 0 fumbles recovered | |
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| RCB | Eric Wright | 26 | 4 | 16 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
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| SS | Amari Spievey | 23 | 1 | 15 | 1.0 sacks, 3 interceptions, 1 fumble recovered | |
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| FS | Louis Delmas | 24 | 2 | 11 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
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Roster