12 Regular Season Pick Sixes
6 Go-Ahead, Long of 79 yards
| 2012 | 3 |
| 2016 | 3 |
| 2014 | 1 |
| 2018 | 1 |
| 2011 | 1 |
| Bears | 3 |
| Steelers | 1 |
| Buccaneers | 1 |
| Broncos | 1 |
| Saints | 1 |
| Home | 9 |
| Road | 3 |
| Sunday | 9 |
| Thursday | 2 |
| Monday | 1 |
| 2nd | 6 |
| 3rd | 2 |
| 4th | 2 |
| 1st | 2 |
| 30 or more yards | 7 |
| 20-29 yards | 2 |
| 10-19 yards | 2 |
| 4-9 yards | 1 |
Regular Season
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2011 | 2011-10-02 | 4 | 4 | CHI | CAR | W 34-29 | 1 | 20 | D.J. Moore | Tied 3-3 | Lead 10-3* | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 2 | 2012 | 2012-10-28 | 7 | 8 | CHI | CAR | W 23-22 | 4 | 25 | Tim Jennings | Trail 14-19 | Lead 20-19* | |
| 3 | 2012 | 2012-11-11 | 9 | 10 | DEN | @ | CAR | W 36-14 | 3 | 40 | Tony Carter | Lead 17-7 | Lead 24-7 |
| 4 | 2012 | 2012-12-30 | 16 | 17 | NOR | CAR | L 38-44 | 2 | 18 | Jonathan Vilma | Trail 7-10 | Lead 14-10* | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 5 | 2014 | 2014-11-10 | 9 | 10 | PHI | CAR | W 45-21 | 2 | 34 | Bradley Fletcher | Lead 24-7 | Lead 31-7 | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 6 | 2016 | 2016-11-13 | 9 | 10 | KAN | @ | CAR | W 20-17 | 4 | 42 | Eric Berry | Trail 6-17 | Trail 14-17 |
| 7 | 2016 | 2016-11-27 | 11 | 12 | OAK | CAR | W 35-32 | 2 | 6 | Khalil Mack | Lead 17-7 | Lead 24-7 | |
| 8 | 2016 | 2017-01-01 | 16 | 17 | TAM | CAR | W 17-16 | 3 | 31 | Brent Grimes | Trail 3-7 | Lead 10-7* | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 9 | 2017 | 2017-10-22 | 7 | 7 | CHI | CAR | W 17-3 | 2 | 76 | Eddie Jackson | Lead 7-0 | Lead 14-0 | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 10 | 2018 | 2018-11-08 | 9 | 10 | PIT | CAR | W 52-21 | 1 | 17 | Vince Williams | Tied 7-7 | Lead 14-7* | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 11 | 2020 | 2020-12-10 | 13 | 14 | LAR | NWE | W 24-3 | 2 | 79 | Kenny Young | Lead 10-0 | Lead 17-0 | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 12 | 2021 | 2021-12-12 | 13 | 14 | ATL | @ | CAR | W 29-21 | 2 | 66 | Mykal Walker | Tied 7-7 | Lead 14-7* |
Playoffs
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2014 | 2015-01-10 | 17 | 19 | SEA | CAR | W 31-17 | 4 | 90 | Kam Chancellor | Lead 24-10 | Lead 31-10 |
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