| Offensive Starters | | | | | |
|---|
| QB | Kyler Murray | 25 | 3 | 11 | 259 for 390, 2,368 yards, 14 td, 7 int, & 67 rushes for 418 yards and 3 td | |
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| RB | James Conner | 27 | 5 | 13 | 183 rushes for 782 yards, 7 td, & 46 catches for 300 yards and 1 td | |
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| WR | Marquise Brown | 25 | 3 | 10 | 67 catches for 709 yards, 3 td, & 1 rush for 1 yards and 0 td | |
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| WR | A.J. Green | 34 | 11 | 10 | 24 catches for 236 yards, 2 td | |
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| TE | Zach Ertz | 32 | 9 | 10 | 47 catches for 406 yards, 4 td | |
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| TE | Trey McBride | 23 | Rook | 13 | 29 catches for 265 yards, 1 td | |
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| LT | Josh Jones | 25 | 2 | 9 | | |
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| LG | Max Garcia | 31 | 7 | 7 | | |
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| C | Billy Price | 28 | 4 | 11 | | |
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| RG | Will Hernandez | 27 | 4 | 13 | | |
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| RT | Kelvin Beachum | 33 | 10 | 17 | 1 fumble recovered | |
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| Defensive Starters | | | | | |
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| LDE | J.J. Watt | 33 | 11 | 16 | 12.5 sacks, 0 interceptions, 1 fumble recovered | |
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| DT | Zach Allen | 25 | 3 | 13 | | |
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| NT | Leki Fotu | 24 | 2 | 9 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
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| LOLB | Myjai Sanders | 24 | Rook | 4 | 3.0 sacks, 0 interceptions, 1 fumble recovered | |
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| LILB | Isaiah Simmons | 24 | 2 | 13 | 4.0 sacks, 2 interceptions, 1 fumble recovered | |
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| RILB | Zaven Collins | 23 | 1 | 16 | 2.0 sacks, 1 interception, 0 fumbles recovered | |
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| ROLB | Markus Golden | 31 | 7 | 14 | 2.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LCB | Byron Murphy | 24 | 3 | 9 | 0.5 sacks, 0 interceptions, 2 fumbles recovered | |
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| RCB | Marco Wilson | 23 | 1 | 13 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | |
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| SS | Jalen Thompson | 24 | 3 | 17 | 0.0 sacks, 1 interception, 1 fumble recovered | |
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| FS | Budda Baker* | 26 | 5 | 15 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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Roster