| Offensive Starters | | | | | |
|---|
| QB | Josh Allen | 27 | 5 | 17 | 385 for 579, 4,306 yards, 29 td, 18 int, & 111 rushes for 524 yards and 15 td | |
|---|
| RB | James Cook* | 24 | 1 | 13 | 237 rushes for 1,122 yards, 2 td, & 44 catches for 445 yards and 4 td | |
|---|
| WR | Gabriel Davis | 24 | 3 | 17 | 45 catches for 746 yards, 7 td, & 1 rush for -2 yards and 0 td | |
|---|
| WR | Stefon Diggs* | 30 | 8 | 17 | 107 catches for 1,183 yards, 8 td, & 1 rush for 5 yards and 0 td | |
|---|
| WR | Khalil Shakir | 23 | 1 | 10 | 39 catches for 611 yards, 2 td, & 1 rush for 10 yards and 0 td | |
|---|
| TE | Dawson Knox | 27 | 4 | 11 | 22 catches for 186 yards, 2 td | |
|---|
| LT | Dion Dawkins* | 29 | 6 | 17 | | |
|---|
| LG | Connor McGovern | 26 | 3 | 17 | 1 fumble recovered | |
|---|
| C | Mitch Morse | 31 | 8 | 17 | | |
|---|
| RG | O'Cyrus Torrence | 23 | Rook | 17 | 1 fumble recovered | |
|---|
| RT | Spencer Brown | 25 | 2 | 17 | | |
|---|
| Defensive Starters | | | | | |
|---|
| LDE | Gregory Rousseau | 23 | 2 | 16 | 5.0 sacks, 0 interceptions, 1 fumble recovered | |
|---|
| LDT | Jordan Phillips | 31 | 8 | 9 | 2.5 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| RDT | Ed Oliver | 26 | 4 | 16 | 9.5 sacks, 1 interception, 0 fumbles recovered | |
|---|
| RDE | Leonard Floyd | 31 | 7 | 16 | 10.5 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| LLB | Tyrel Dodson | 25 | 3 | 10 | 2.5 sacks, 0 interceptions, 1 fumble recovered | |
|---|
| MLB | Terrel Bernard | 24 | 1 | 17 | 6.5 sacks, 3 interceptions, 3 fumbles recovered | |
|---|
| LCB | Rasul Douglas | 28 | 6 | 8 | 1.0 sacks, 4 interceptions, 2 fumbles recovered | |
|---|
| RCB | Christian Benford | 23 | 1 | 14 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
|---|
| SS | Jordan Poyer | 32 | 10 | 16 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| FS | Micah Hyde | 33 | 10 | 14 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
|---|
| DB | Taron Johnson | 27 | 5 | 17 | | |
|---|
Roster